ataxia telangiectasia造句
例句与造句
- For instance two dominant-negative germ line mutations were identified in the Ataxia telangiectasia mutated ( ATM ) gene which increases susceptibility to breast cancer.
- In a randomized controlled trial betamethasone was shown to reduce some of the ataxia symptoms associated with ataxia telangiectasia ( A-T ) by 28-31 %.
- In the presence of ionizing radiation ( IR ), the Smc1 subunit of cohesin is phosphorylated by the ataxia telangiectasia mutated ( ATM ) kinase.
- Even though ataxia telangiectasia is an autosomal recessive disorder, people who are heterozygotes for this still have an increased risk of developing a lymphoproliferative disorder.
- The cancers associated with the gene, called the ATM ( for ataxia telangiectasia mutated ), include those of the breast, lung, stomach, skin and pancreas.
- It's difficult to find ataxia telangiectasia in a sentence. 用ataxia telangiectasia造句挺难的
- Repair of these presumably difficult-to-rejoin breaks also requires several other proteins, including the Mre11 / Rad50 / NBS1 complex, the ataxia telangiectasia-mutated ATM kinase, and 53BP1.
- The gene also causes a fatal disease, ataxia telangiectasia, in the 1 in 40, 000 people who inherit two copies of it, one from each parent.
- In the case of ataxia telangiectasia, however, scientists had been interested in the gene for years because they thought it might provide clues to the development of cancer.
- EZH2 has been targeted for inhibition because it is upregulated in multiple cancers including, but not limited to, breast, neurodegenerative symptoms in the nervous system disorder, ataxia telangiectasia.
- The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 ( breast cancer 1 ) protein and the ATM ( ataxia telangiectasia mutated ) protein.
- Ataxia telangiectasia mutated ( ATM ) is a kinase that ( similar to mTOR ) can phosphorylate KAP1 resulting in the switch from viral latency to the lytic cycle.
- Some disorders that predispose a person to lymphoproliferative disorders are severe combined immuno deficiency ( SCID ), Ch閐iak-Higashi syndrome, Wiskott-Aldrich syndrome ( an X-linked recessive disorder ), and ataxia telangiectasia.
- For example, scientists found the gene for a rare disease in children called ataxia telangiectasia, or AT, and created transgenic mice they hoped would serve as models for the human disease.
- Defects in the ATM gene are known to cause a syndrome called ataxia telangiectasia, or A-T, which is characterized by stunted growth, immune disorders, neurological deficits and cancers like leukemia and lymphoma.
- Ataxia telangiectasia results from defects in the ataxia telangiectasia mutated gene, which can cause abnormal cell death in various places of the body, including brain areas related to coordinated movement of the eyes.
